Nonlinear energy harvesting based on a rotating system

Acknowledgement The authors acknowledge the financial supports of the National Natural Science Foundation of China (No.11702111, 11732014,11872201, 12172166) and the State Scholarship Fund of CSCPeer reviewedPostprin

Mechanical Deformation Induced Continuously Variable Emission for Radiative Cooling

Passive radiative cooling drawing the heat energy of objects to the cold outer space through the atmospheric transparent window (8 um - 13 um) is significant for reducing the energy consumption of buildings. Daytime and nighttime radiative cooling have been extensively investigated in the past. However, radiative cooling which can continuously regulate its cooling temperature, like a valve, according to human need is rarely reported. In this study, we present a concept of reconfigurable photonic structure for the adaptive radiative cooling by continuously varying the emission spectra in the atmospheric window region. This is realized by the deformation of the one-dimensional PDMS grating and the nanoparticles embedded PDMS thin film when subjected to mechanical strain. The proposed structure reaches different stagnation temperatures under certain strains. A dynamic exchange between two different strains results in the fluctuation of the photonic structure's temperature around a set temperature

A Generative Approach for Script Event Prediction via Contrastive Fine-tuning

Script event prediction aims to predict the subsequent event given the context. This requires the capability to infer the correlations between events. Recent works have attempted to improve event correlation reasoning by using pretrained language models and incorporating external knowledge~(e.g., discourse relations). Though promising results have been achieved, some challenges still remain. First, the pretrained language models adopted by current works ignore event-level knowledge, resulting in an inability to capture the correlations between events well. Second, modeling correlations between events with discourse relations is limited because it can only capture explicit correlations between events with discourse markers, and cannot capture many implicit correlations. To this end, we propose a novel generative approach for this task, in which a pretrained language model is fine-tuned with an event-centric pretraining objective and predicts the next event within a generative paradigm. Specifically, we first introduce a novel event-level blank infilling strategy as the learning objective to inject event-level knowledge into the pretrained language model, and then design a likelihood-based contrastive loss for fine-tuning the generative model. Instead of using an additional prediction layer, we perform prediction by using sequence likelihoods generated by the generative model. Our approach models correlations between events in a soft way without any external knowledge. The likelihood-based prediction eliminates the need to use additional networks to make predictions and is somewhat interpretable since it scores each word in the event. Experimental results on the multi-choice narrative cloze~(MCNC) task demonstrate that our approach achieves better results than other state-of-the-art baselines. Our code will be available at https://github.com/zhufq00/mcnc

Identification and characterization of bone/cartilage-associated signatures in common fibrotic skin diseases

Background: Fibrotic skin diseases are characterized by excessive accumulation of the extracellular matrix (ECM) and activation of fibroblasts, leading to a global healthcare burden. However, effective treatments of fibrotic skin diseases remain limited, and their pathological mechanisms require further investigation. This study aims to investigate the common biomarkers and therapeutic targets in two major fibrotic skin diseases, namely, keloid and systemic sclerosis (SSc), by bioinformatics analysis.Methods: The keloid (GSE92566) and SSc (GSE95065) datasets were downloaded from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were identified, followed by functional enrichment analysis using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). We then constructed a protein–protein interaction (PPI) network for the identification of hub genes. We explored the possibility of further functional enrichment analysis of hub genes on the Metascape, GeneMANIA, and TissueNexus platforms. Transcription factor (TF)–hub gene and miRNA–hub gene networks were established using NetworkAnalyst. We fixed GSE90051 and GSE76855 as the external validation datasets. Student’s t-test and receiver operating characteristic (ROC) curve were used for candidate hub gene validation. Hub gene expression was assessed in vitro by quantitative real-time PCR.Results: A total of 157 overlapping DEGs (ODEGs) were retrieved from the GSE92566 and GSE95065 datasets, and five hub genes (COL11A1, COL5A2, ASPN, COL10A1, and COMP) were identified and validated. Functional studies revealed that hub genes were predominantly enriched in bone/cartilage-related and collagen-related processes. FOXC1 and miR-335-5p were predicted to be master regulators at both transcriptional and post‐transcriptional levels.Conclusion: COL11A1, COL5A2, ASPN, COL10A1, and COMP may help understand the pathological mechanism of the major fibrotic skin diseases; moreover, FOXC1 and miR-355-5p could build a regulatory network in keloid and SSc